I still haven't even done a marathon, but based on doing the relay once at this event (five person 100k), if I ever did a 50k I would try this one. They offer a 50M.
http://www.dwdhell.com/packet11/2011MI_ultramap.pd...Not as epic as Bash's, but only five hours from Toronto by car. No monster hills. Lots of small ones (a few too steep to run), and lots of mud, river crossings, etc. Not a repeated loop or out and back, although a few sections are reused as you route around. It looks like sections are on southeast Michigan's finest mountain bike trail. Half of our good o maps are either this park or adjacent to it.